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Unless a pacemaker is present, beta blockers can severely depress conduction in the AV node, resulting in a reduction of heart rate and cardiac output. One should be very cautious with the use of beta blockers in tachycardia patients with Wolff-Parkinson-White Syndrome, as it can result in life-threatening arrhythmia in certain patients.
Sotalol is a beta blocker and non-selectively binds to both β 1-and β 2-adrenergic receptors preventing activation of the receptors by their stimulatory ligand (catecholamines). [ 11 ] [ 12 ] It has no intrinsic sympathomimetic activity .
Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [7] and used for cardiovascular diseases, [7] including tachyarrhythmias, high blood pressure, angina, and heart failure.
What is a beta blocker? Churchwell said the drug class slows the heart by inhibiting and binding to beta one and beta two receptors on the heart. They limit the production of epinephrine ...
To manage his AFib, Kaveney’s cardiologist prescribed him a beta blocker, but it suppressed his heart rate so much that it made Kaveney feel weak. ... He was also given a pacemaker implant to ...
They thus reduce the contractility of the heart, so may be inappropriate in heart failure. However, in contrast to beta blockers, they allow the body to retain adrenergic control of heart rate and contractility. [citation needed] Class IV agents include verapamil and diltiazem.
Ivabradine acts by allowing negative chronotropy in the sinoatrial structure, thus reducing the heart rate via specific inhibition of the pacemaker current. It operates by a mechanism different from that of beta blockers and calcium channel blockers, which are two commonly prescribed antianginal classes of cardiac drugs. Ivabradine has no ...
Carvedilol, sold under the brand name Coreg among others, is a beta blocker medication, that may be prescribed for the treatment of high blood pressure (hypertension) and chronic heart failure with reduced ejection fraction (also known as HFrEF or systolic heart failure).