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In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B 6, B 9, and B 12. [3] High levels of homocysteine in the blood (hyperhomocysteinemia) is regarded as a marker of cardiovascular disease, likely working through atherogenesis, which can result in ischemic injury.
As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B 6, folic acid (vitamin B 9), and vitamin B 12 can lead to high homocysteine levels. [2] Other possible causes of hyperhomocysteinemia include genetics, excessive methionine intake, and other diseases. [3]
Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2] Normal blood levels are considered to be at least above 300 pg/mL in adults. [2] Some researchers have suggested that current standards for vitamin B 12 levels are too low. [152]
Opt for nuts to balance out other high-carb ingredients, or better yet, instead of empty high-calorie snacks such as potato and corn chips. panco971/istockphoto Flax Seeds
The vitamin is then transferred to TC2, which serves as the circulating plasma transporter, hereditary defects in the production of TC2 and its receptor may produce functional deficiencies in B 12 and infantile megaloblastic anemia, and abnormal B 12 related biochemistry, even in some cases with normal blood B 12 levels. For the vitamin to ...
Homocysteine is elevated (5-MTHF is used to convert homocysteine to methionine) as in vitamin B 12 deficiency, whereas methylmalonic acid is normal (elevated in vitamin B 12 deficiency). [citation needed] More specifically, according to a 2014 UK guideline, [30] A serum folate level of less than 7 nmol/L (3 μg/L) is indicative of folate ...
“Vitamin B12 is necessary for normal processing of carbs, proteins, and fats in the body and for the normal formation of red blood cells,” adds Elizabeth Somer, M.S., R.D.N., a dietitian based ...
The Recommended Dietary Allowance (RDA) for vitamin B12 is 0.9-2.4 μg/day, while the estimated average requirement in the U.S. and Canada is 0.7-2 μg/day. Elderly individuals with plasma vitamin B12 levels below 148 pmol/L are considered severely deficient, and those with levels between 148 and 221 pmol/L are marginally deficient.
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