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Canesten brand Clotrimazole antifungal cream. Clotrimazole is available as a generic medication, [2] and in 2016 Canesten brand Clotrimazole was one of the biggest-selling branded over-the-counter medications sold in Great Britain, with sales of £39.2 million. [20]
Bifonazole (trade name Canespor among others [1]) is an imidazole antifungal drug used in form of ointments. It was patented in 1974 and approved for medical use in 1983. [2] There are also combinations with carbamide for the treatment of onychomycosis.
Burow's solution is an aqueous solution of aluminium triacetate. It is available in the U.S. as an over-the-counter drug for topical administration , with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [ 1 ]
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10]
Granulomatous meningoencephalitis (GME) is an inflammatory disease of the central nervous system (CNS) of dogs and, rarely, cats.It is a form of meningoencephalitis.GME is likely second only to encephalitis caused by canine distemper virus as the most common cause of inflammatory disease of the canine CNS. [1]
The law required that all drugs introduced between 1938 and 1962 had to be effective. A collaborative study by the U.S. Food and Drug Administration and the National Academy of Sciences showed that nearly 40 percent of these products were not effective. A similarly comprehensive study of over-the-counter products began ten years later. [70]
Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. [12] [4] [6] [13] It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs.
Concentrated solutions are toxic to humans, causing corrosion/irritation to the skin and mucosa, and death if taken internally in sufficient volumes. 0.1% is the maximum concentration of benzalkonium chloride that does not produce primary irritation on intact skin or act as a sensitizer. [43]
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