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Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm. Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1).
The appearance of a prematurely condensed chromosome depends on the stage that the interphase cell was in. [1] Chromosomes that are condensed during the G 1 phase are usually long and have a single strand, while chromosomes condensed during the S phase appear crushed. Condensation during the G 2 phase yields long chromosomes with two chromatids.
This is an accepted version of this page This is the latest accepted revision, reviewed on 10 February 2025. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
Metaphase chromosomes make the classical picture of chromosomes . For classical cytogenetic analyses, cells are grown in short term culture and arrested in metaphase using mitotic inhibitor . Further they are used for slide preparation and banding ( staining ) of chromosomes to be visualised under microscope to study structure and number of ...
Various DNA stains are used to treat cells such that condensing chromosomes can be visualized as the move through prophase. [4] The giemsa G-banding technique is commonly used to identify mammalian chromosomes, but utilizing the technology on plant cells was originally difficult due to the high degree of chromosome compaction in plant cells.
Condensation of long double-helical DNAs is a sharp phase transition, which takes place within a narrow interval of condensing agent concentrations.[ref] Since the double helices come very closely to each other in the condensed phase, this leads to the restructuring of water molecules, which gives rise to the so-called hydration forces.[ref] To ...
The interaction between the two types of loops is evident in mitosis. While positive feedback initiates mitosis, a negative feedback loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex. This example clearly shows the combined effects that positive and negative feedback loops have on cell-cycle ...
Cell division in prokaryotes (binary fission) and eukaryotes (mitosis and meiosis). The thick lines are chromosomes, and the thin blue lines are fibers pulling on the chromosomes and pushing the ends of the cell apart. The cell cycle in eukaryotes: I = Interphase, M = Mitosis, G 0 = Gap 0, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis, G 3 = Gap 3.