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Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.
In HSV-1-infected individuals, seroconversion after an oral infection helps prevent additional HSV-1 infections such as whitlow, genital herpes, and herpes of the eye. Prior HSV-1 seroconversion seems to reduce the symptoms of a later HSV-2 infection, although HSV-2 can still be contracted.
It is estimated to affect at least 1 in 500,000 individuals per year, [1] and some studies suggest an incidence rate of 5.9 cases per 100,000 live births. [2] About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores.
More than 3.7 billion people under the age of 50 suffer from the herpes simplex virus type 1 (HSV-1), usually after catching it in childhood.
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [1] When symptoms do occur, they typically include small blisters that break open to form painful ulcers. [1]
Infection by the type 1 strain of herpes simplex virus (HSV-1) is most common; however, cases of oral infection by the type 2 strain are increasing. [14] Oral HSV-2 shedding is rare, and "usually noted in the context of first episode genital herpes." [21] In general, both types can cause oral or genital herpes. [22] [23] [24]
Herpetic gingivostomatitis is an infection caused by the herpes simplex virus (HSV). The HSV is a double-stranded DNA virus categorised into two types; HSV-1 and HSV-2.HSV-1 is predominantly responsible for oral, facial and ocular infections whereas HSV-2 is responsible for most genital and cutaneous lower herpetic lesions.
Herpes simplex virus 1 (HHV-1 or HSV-1) is a species of virus in the genus Simplexvirus, subfamily Alphaherpesvirinae, family Herpesviridae, and order Herpesvirales. [ 1 ] [ 2 ] Evolution
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