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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Congenital insensitivity to pain (CIP), also known as congenital analgesia, is one or more extraordinarily rare conditions in which a person cannot feel (and has never felt) physical pain. [1] The conditions described here are separate from the HSAN group of disorders, which have more specific signs and cause.

  3. Marsili syndrome - Wikipedia

    en.wikipedia.org/wiki/Marsili_syndrome

    1960: Ervin and Sternbach describe 6 members from a 2-generation family with dominantly-inherited congenital insensitivity to pain. [ 4 ] 1974: Comings and Amromin describe 3 members from a 2-generation family which consisted of a mother, her son and her daughter with the symptoms characteristic of Marsili syndrome, there was a possibility that ...

  4. A Life Without Pain - Wikipedia

    en.wikipedia.org/wiki/A_Life_Without_Pain

    The film explores the daily lives of three children with Congenital insensitivity to pain, a rare genetic disorder shared by just a hundred people in the world. [2] Three-year-old Gabby from Minnesota, 7-year-old Miriam from Norway and 10-year-old Jamilah from Germany have to be carefully guarded by their parents so they don't suffer serious, life-altering injuries.

  5. Hypoalgesia - Wikipedia

    en.wikipedia.org/wiki/Hypoalgesia

    In the case of hypoalgesia, a decreased response to pain would be very beneficial in a situation where an organism's life was at stake, since feeling pain would be a hindrance rather than a help. It has been well documented that fear does cause a decrease in pain response, [ 6 ] however much like the exercise induced hypoalgesia, the exact ...

  6. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to a lack of protective impulses. [4] Joint and bone problems are common due to repeated injuries, and wounds heal poorly. [5]

  7. Eradication of suffering - Wikipedia

    en.wikipedia.org/wiki/Eradication_of_suffering

    Opposition to anesthesia has since dissipated; however, the prospect of eradicating pain raises similar concerns about interfering with life's natural functions. [ 2 ] People who are naturally incapable of feeling pain or unpleasant sensations due to rare conditions like pain asymbolia or congenital insensitivity to pain have been studied to ...

  8. Familial dysautonomia - Wikipedia

    en.wikipedia.org/wiki/Familial_dysautonomia

    Familial dysautonomia (FD), also known as Riley–Day syndrome, is a rare, [2] progressive, [3] recessive genetic disorder of the autonomic nervous system [2] that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system.

  9. Talk : Congenital insensitivity to pain with anhidrosis

    en.wikipedia.org/wiki/Talk:Congenital...

    Here are links to possibly useful sources of information about Congenital insensitivity to pain with anhidrosis. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine.