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Common side effects include dizziness, sleepiness, swelling, nausea, shortness of breath, and abdominal pain. [2] Severe side effects may include low blood pressure with standing, an irregular heart beat, and priapism. [2] [3] It is a selective α 1-adrenergic blocker in the quinazoline class of compounds. [2]
The UpToDate system is an evidence-based clinical resource. It includes a collection of medical and patient information, access to Lexicomp drug monographs and drug-to-drug interactions, and a number of medical calculators. UpToDate is written by over 7,100 physician authors, editors, and peer reviewers. It is available both via the Internet ...
In the United States, anti-aging products are commonly marketed with false health claims, and are deemed to be among various scams on consumers. [3] [4] Since 2007, the US Food and Drug Administration (FDA) has issued dozens of warning letters to manufacturers of skin care products with false marketing – including supposed anti-aging effects – about the benefits of such products, which are ...
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Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Beneficial side effects are less common; some examples, in many cases of side-effects that ultimately gained regulatory approval as intended effects, are: Bevacizumab ( Avastin ), used to slow the growth of blood vessels, has been used against dry age-related macular degeneration , as well as macular edema from diseases such as diabetic ...
The PRISMA flow diagram, depicting the flow of information through the different phases of a systematic review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an evidence-based minimum set of items aimed at helping scientific authors to report a wide array of systematic reviews and meta-analyses, primarily used to assess the benefits and harms of a health care ...
The U.S. Centers for Disease Control and Prevention is seeking to withdraw all papers involving its researchers that are being considered for publication by external scientific journals to allow ...
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