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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Qsymia (phentermine-topiramate) ... Topamax (topiramate) A healthcare provider can walk you through the pros and cons of each medication and help you decide which one may be most suitable for you.
Phentermine is a substituted amphetamine and topiramate has an unknown mechanism of action Approved for weight management (short-term) by the FDA but not the European Medicines Agency [ 54 ] 10% [ 55 ] or 8.25 kilograms (18.2 lb) [ 56 ]
Qsymia® (phentermine-topiramate) And there are lifestyle changes you can make to lose weight, such as: Eating nutritious foods. Load up on fruits, vegetables, legumes, whole grains, and lean protein.
If you take Qsymia, the starting dose is 3.75mg of phentermine and 23mg of topiramate daily for 14 days. The dose then increases to 7.5mg of phentermine and 46mg of topiramate daily for 90 days.
Amphetamine [note 2] (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
During a recent appearance on “The Howard Stern Show," the comedian, 43, opened up about her scary experience trying the medication for weight-loss purposes.
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