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Cerebral perfusion pressure, or CPP, is the net pressure gradient causing cerebral blood flow to the brain (brain perfusion).It must be maintained within narrow limits because too little pressure could cause brain tissue to become ischemic (having inadequate blood flow), and too much could raise intracranial pressure (ICP).
1.2–2.9 [75] μg/L [5] [15] or ng/mL [23] More detailed cutoffs in PSA – Serum levels: 70–79 years, non-African-American: 4.0–9.0 [75] 70–79 years, African-American: 7.7–13 [75] PAP: 3 [23] units/dL (Bodansky units) Calcitonin: 5, [76] 15 [76] ng/L or pg/mL: Cutoff against medullary thyroid cancer [76] More detailed cutoffs in ...
This part of coronary circulatory regulation is known as auto regulation and it occurs over a plateau, reflecting the constant blood flow at varying CPP & resistance. The slope of a CBF (coronary blood flow) vs. CPP graph gives 1/Resistance. Autoregulation maintains a normal blood flow within the pressure range of 70–110 mm Hg.
[3] [44] [45] Bolus doses, particularly at higher concentrations, for example 23.4%, are effective at reducing ICP and improving cerebral perfusion pressure. [ 44 ] [ 46 ] In traumatic brain injuries , a responsiveness to hypertonic saline lasting greater than 2 hours was associated with decreased chance of death and improved neurologic ...
The disease burden is more concentrated in Africa, Asia, and South America. [75] A study in 2019 estimated that there are 180,000 childhood hydrocephalus cases from the African continent per year. It also reported 90,000 cases from Southeast Asia and the Western Pacific. [75] Congenital hydrocephalus was found to be associated with many factors ...
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury and at rest, is normally 7–15 mmHg for a supine adult.
There is an ongoing medical debate over what is the optimal level of blood pressure to target when using drugs to lower blood pressure with hypertension, particularly in older people. [ 13 ] Blood pressure fluctuates from minute to minute and normally shows a circadian rhythm over a 24-hour period, [ 14 ] with highest readings in the early ...
The youngest mother on record is Lina Medina, who gave birth at the age of either 5 years, 7 months and 17 days [11] or 6 years 5 months as mentioned in another report. [ 12 ] "Central precocious puberty (CPP) was reported in some patients with suprasellar arachnoid cysts (SAC), and SCFE ( slipped capital femoral epiphysis ) occurs in patients ...