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  2. Esophageal spasm - Wikipedia

    en.wikipedia.org/wiki/Esophageal_spasm

    Esophageal spasm is a disorder of motility of the esophagus. [2] There are two types of esophageal spasm: [2] Diffuse or distal esophageal spasm (DES), where there is uncoordinated esophageal contractions; Nutcracker esophagus (NE) also known as hypertensive peristalsis, where the contractions are coordinated but with an excessive amplitude.

  3. Esophageal motility disorder - Wikipedia

    en.wikipedia.org/wiki/Esophageal_motility_disorder

    Diffuse esophageal spasm; Nutcracker esophagus; Hypertensive lower esophageal sphincter; An esophageal motility disorder can also be secondary to other diseases. [1] For example, it may be a result of CREST syndrome, referring to the five main features: calcinosis, Raynaud syndrome, esophageal dysmotility, sclerodactyly and telangiectasia. [2]

  4. Diffuse esophageal spasm - Wikipedia

    en.wikipedia.org/wiki/Diffuse_esophageal_spasm

    Diffuse esophageal spasm (DES), also known as distal esophageal spasm, is a condition characterized by uncoordinated contractions of the esophagus, which may cause difficulty swallowing or regurgitation. In some cases, it may cause symptoms such as chest pain, similar to heart disease. In many cases, the cause of DES remains unknown.

  5. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    The modern period, beginning in 1920, saw major developments in research into the cause and treatment of discoid and systemic lupus. Research conducted in the 1920s and 1930s led to the first detailed pathologic descriptions of lupus and demonstrated how the disease affected the kidney, heart, and lung tissue. [ 165 ]

  6. Scientists say they have identified lupus' root cause — and ...

    www.aol.com/news/scientists-identified-lupus...

    Scientists say they have identified lupus' root cause — and it could pave the way for new treatment ... Around 90% of people with lupus are women. Common symptoms include extreme fatigue, joint ...

  7. Nutcracker esophagus - Wikipedia

    en.wikipedia.org/wiki/Nutcracker_esophagus

    Nutcracker esophagus is one of several motility disorders of the esophagus, including achalasia and diffuse esophageal spasm. It causes difficulty swallowing with both solid and liquid foods, and can cause significant chest pain; it may also be asymptomatic. Nutcracker esophagus can affect people of any age but is more common in the sixth and ...

  8. Roivant Sciences' lupus drug fails to reduce symptoms in mid ...

    www.aol.com/news/roivant-sciences-lupus-drug...

    The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...

  9. Esophageal dysphagia - Wikipedia

    en.wikipedia.org/wiki/Esophageal_dysphagia

    Rings cause intermittent mechanical dysphagia, meaning patients will usually present with transient discomfort and regurgitation while swallowing solids and then liquids, depending on the constriction of the ring. Webs--- Usually squamous mucosal protrusion into the esophageal lumen, especially anterior cervical esophagus behind the cricoid ...