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The earliest oral treatment for hypothyroidism consisted of thyroid extract. George Redmayne Murray of the United Kingdom first described treatment of myxedema with thyroid extract in 1891, and published a description of long-term successful treatment (28 years) of a patient with myxedema (severe hypothyroidism) in 1920 [ 17 ] His treatment was ...
Levothyroxine is typically used to treat hypothyroidism, [12] and is the treatment of choice for people with hypothyroidism [13] who often require lifelong thyroid hormone therapy. [14] It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), which is considered goiter-inducing.
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.
Hypothyroidism is more common in women than in men. [3] People over the age of 60 are more commonly affected. [3] Dogs are also known to develop hypothyroidism, as are cats and horses, albeit more rarely. [13] The word hypothyroidism is from Greek hypo-'reduced', thyreos 'shield', and eidos 'form', where the two latter parts refer to the ...
It is most commonly used to treat hypothyroidism and myxedema coma. [2] It can be taken by mouth or by injection into a vein. [2] Side effects may occur from excessive doses. [2] This may include weight loss, fever, headache, anxiety, trouble sleeping, arrhythmias, and heart failure. [2] Use in pregnancy and breastfeeding is generally safe. [3] [2]
Primary treatment is prompted by the administration of adequate doses of either the thyroid hormone L-thyroxine given intravenously or by giving liothyronine via a nasogastric tube. It is essential to identify and treat the condition precipitating the coma. [9] Myxedema coma is rare but often fatal.
In Graves' disease, treatment with antithyroid medications must be given for six months to two years, in order to be effective. Even then, upon cessation of the drugs, the hyperthyroid state may recur. Side effects of the antithyroid medications include a potentially fatal reduction in the level of white blood cells.
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