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  2. US FDA grants full approval to AbbVie's ovarian cancer therapy

    www.aol.com/news/us-fda-grants-full-approval...

    (Reuters) -The U.S. Food and Drug Administration said on Friday it had granted traditional approval for AbbVie's "guided missile" cancer therapy, Elahere, for patients with a type of ovarian ...

  3. Olaparib - Wikipedia

    en.wikipedia.org/wiki/Olaparib

    The FDA approval was for germline BRCA mutated (gBRCAm) advanced ovarian cancer that has received three or more prior lines of chemotherapy. [7] In January 2018, olaparib became the first PARP inhibitor to be approved by the FDA for gBRCAm metastatic breast cancer.

  4. Pafolacianine - Wikipedia

    en.wikipedia.org/wiki/Pafolacianine

    Scientists from Purdue University designed and developed OTL38 and licensed it to On Target Laboratories in 2013. [9] [10] The safety and effectiveness of pafolacianine was evaluated in a randomized, multi-center, open-label study of women diagnosed with ovarian cancer or with high clinical suspicion of ovarian cancer who were scheduled to undergo surgery.

  5. Mirvetuximab soravtansine - Wikipedia

    en.wikipedia.org/wiki/Mirvetuximab_soravtansine

    Mirvetuximab soravtansine is indicated for the treatment of adults with folate receptor alpha (FRα) positive, platinum-resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer, who have received one to three prior systemic treatment regimens. [2] [5] [6] Recipients are selected for therapy based on an FDA ...

  6. AstraZeneca-Merck Ovarian Cancer Treatment Gets FDA Approval

    www.aol.com/news/astrazeneca-merck-ovarian...

    The U.S. Food and Drug Administration (FDA) approved a treatment developed by AstraZeneca (AZN) and Merck Co. (MRK) for advanced ovarian cancer.The FDA approved the ovarian drug Lynparza to be ...

  7. PARP inhibitor - Wikipedia

    en.wikipedia.org/wiki/PARP_inhibitor

    In April 2018 it was granted FDA approval. Niraparib: In March 2017 approved by US FDA for epithelial ovarian, fallopian tube, and primary peritoneal cancer. [9] [10] Inhibitor of PARP1 and PARP2. [11] Talazoparib was approved in 2018 by US FDA for breast cancer with germline BRCA mutations. [12]

  8. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    recurrent ovarian cancer responsive to platinum-based chemotherapy Ocrelizumab [2] Genentech: multiple sclerosis: Dupilumab [2] Regeneron Pharmaceuticals: atopic dermatitis: Palbociclib [2] Pfizer: HR-positive, HER2-negative breast cancer Valbenazine [2] Neurocrine Biosciences: tardive dyskinesia: Ranibizumab [2] Genentech: diabetic retinopathy ...

  9. Tesaro - Wikipedia

    en.wikipedia.org/wiki/Tesaro

    The company's product Niraparib was granted priority review and was given a target action date of June 2017 by the FDA. [4] In March 2017, Tesaro won approval for its drug Zejula to treat ovarian cancer. [5] On May 31, 2017, it was reported that Tesaro Inc. was exploring a sale. [5]

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