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Cystic kidney disease. Cystic kidney disease refers to a wide range of hereditary, developmental, and acquired conditions [1] and with the inclusion of neoplasms with cystic changes, over 40 classifications and subtypes have been identified. Depending on the disease classification, the presentation may be at birth, or much later into adult life.
Polycystic kidney disease. Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder [ 5 ][ 6 ] in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. [ 7 ] These cysts may begin to develop in utero, in infancy, in ...
Madin-Darby canine kidney (MDCK) cells are a model mammalian cell line used in biomedical research. MDCK cells are used for a wide variety of cell biology studies including cell polarity , cell-cell adhesions (termed adherens junctions ), collective cell motility, toxicity studies, [ 1 ] as well as responses to growth factors.
Specialty. Medical genetics. Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common, life-threatening inherited human disorders and the most common hereditary kidney disease. [ 1 ][ 2 ] It is associated with large interfamilial and intrafamilial variability, which can be explained to a large extent by its genetic ...
A renal cyst is a fluid collection in or on the kidney. There are several types based on the Bosniak classification. The majority are benign, simple cysts that can be monitored and not intervened upon. However, some are cancerous or are suspicious for cancer and are commonly removed in a surgical procedure called nephrectomy.
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney. Nephritis is an inflammatory kidney disease and has several types according to the location of the inflammation. Inflammation can be diagnosed by blood tests. Nephrosis is non-inflammatory kidney disease.
Kidney failure, also known as end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. [2] Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney ...
The cause of PKD in the Persian is an autosomal dominant mutation to the PKD1 gene. [73] Cysts develop and grow in the kidney over time, replacing kidney tissues and enlarging the kidney. Kidney failure develops later in life, at an average age of 7 years old (ranging from 3 to 10 years old).