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  2. Griffith's experiment - Wikipedia

    en.wikipedia.org/wiki/Griffith's_experiment

    Griffith's experiment, [1] performed by Frederick Griffith and reported in 1928, [2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation. [3][4] Griffith's findings were followed by research in the late 1930s and early 40s that isolated DNA as the material ...

  3. Serial passage - Wikipedia

    en.wikipedia.org/wiki/Serial_passage

    Serial passage is the process of growing bacteria or a virus in iterations. For instance, a virus may be grown in one environment, and then a portion of that virus population can be removed and put into a new environment. This process is repeated with as many stages as desired, and then the final product is studied, often in comparison with the ...

  4. E. coli long-term evolution experiment - Wikipedia

    en.wikipedia.org/wiki/E._coli_long-term...

    The 12 E. coli LTEE populations on June 25, 2008. [1]The E. coli long-term evolution experiment (LTEE) is an ongoing study in experimental evolution begun by Richard Lenski at the University of California, Irvine, carried on by Lenski and colleagues at Michigan State University, [2] and currently overseen by Jeffrey Barrick at the University of Texas at Austin. [3]

  5. Directed evolution - Wikipedia

    en.wikipedia.org/wiki/Directed_evolution

    The outer circle demonstrates steps in a typical experiment. The red symbols indicate functional variants, the pale symbols indicate variants with reduced function. Directed evolution ( DE ) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward a user-defined goal. [ 1 ]

  6. Avery–MacLeod–McCarty experiment - Wikipedia

    en.wikipedia.org/wiki/Avery–MacLeod–McCarty...

    The Avery–MacLeod–McCarty experiment was an experimental demonstration by Oswald Avery, Colin MacLeod, and Maclyn McCarty that, in 1944, reported that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it was proteins that served the function of carrying genetic information (with the ...

  7. Min System - Wikipedia

    en.wikipedia.org/wiki/Min_System

    The Min System is a mechanism composed of three proteins MinC, MinD, and MinE used by E. coli as a means of properly localizing the septum prior to cell division. Each component participates in generating a dynamic oscillation of FtsZ protein inhibition between the two bacterial poles to precisely specify the mid-zone of the cell, allowing the ...

  8. In vitro - Wikipedia

    en.wikipedia.org/wiki/In_vitro

    In vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter ...

  9. Axenic - Wikipedia

    en.wikipedia.org/wiki/Axenic

    Axenic cultures of microorganisms are typically prepared by subculture of an existing mixed culture. This may involve use of a dilution series, in which a culture is successively diluted to the point where subsamples of it contain only a few individual organisms, ideally only a single individual (in the case of an asexual species).