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In Canada, temazepam is a Schedule IV controlled substance requiring a registered doctor's prescription. [86] In Denmark, temazepam is listed as a Class D substance under the Executive Order 698 of 1993 on Euphoric Substances which means it has a high potential for abuse, but is used for medical and scientific purposes. [87]
This is the list of Schedule IV controlled substances in the United States as defined by the Controlled Substances Act. [1] The following findings are required for substances to be placed in this schedule: [2] The drug or other substance has a low potential for abuse relative to the drugs or other substances in schedule III.
Some variation in drug scheduling exists in individual countries; for example, in the United Kingdom, midazolam and temazepam are Schedule III controlled drugs. [217] British law requires that temazepam (but not midazolam) be stored in safe custody. Safe custody requirements ensures that pharmacists and doctors holding stock of temazepam must ...
Flutemazepam was initially first synthesized in 1965, [1] but was not further described until a team at Stabilimenti Chimici Farmaceutici Riuniti SpA in the mid-1970s. [2] [3] It is a short-acting (9–25 hr elimination half-life) fluorinated analogue of temazepam that has powerful hypnotic, sedative, amnesiac, anxiolytic, anticonvulsant and skeletal muscle relaxant properties.
It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and ...
It is the dimethyl carbamate ester of temazepam, a metabolite of diazepam. [3] While it possesses anxiolytic , anticonvulsant , skeletal muscle relaxant and hypnotic properties [ 4 ] it differs from other benzodiazepines in that its anxiolytic properties are particularly prominent but has comparatively limited anticonvulsant , hypnotic and ...
Temazepam abuse and seizures have been falling in the UK probably due to its reclassification as Schedule 3 controlled drug with tighter prescribing restrictions and the resultant reduction in availability. [51] A total of 2.75 million temazepam capsules were seized in the Netherlands by authorities between 1996 and 1999. [52]
Lormetazepam, sold under the brand name Noctamid among others, is a drug which is a short to intermediate acting 3-hydroxy [3] benzodiazepine derivative and temazepam analogue. [4] It possesses hypnotic, anxiolytic, anticonvulsant, sedative, and skeletal muscle relaxant properties. It was patented in 1961 and came into medical use in 1980. [5]