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Among bipolar patients taking anticonvulsants, those on lamotrigine have a better cognitive profile than those on carbamazepine, valproate, topiramate, and zonisamide. [ 36 ] Although decreased verbal memory and slowed psychomotor speed are common side effects of lithium use [ 37 ] [ 38 ] these side effects usually disappear after ...
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...
There was a clear difference between the groups, but the meaning of this in day-to-day care is unclear. MD 5.85 lower (7.8 lower to 3.91 lower) Moderate: Adverse events; Abnormal liver function (blood test changes)* Adding valproate to antipsychotic drug treatment does not clearly cause liver problems.
According to guidelines by the American Academy of Neurology and American Epilepsy Society, [42] mainly based on a major article review in 2004, [43] patients with newly diagnosed epilepsy who require treatment can be initiated on standard anticonvulsants such as carbamazepine, phenytoin, valproic acid/valproate semisodium, phenobarbital, or on ...
Valproate has become a commonly prescribed treatment and effectively treats manic episodes. [144] Carbamazepine is less effective in preventing relapse than lithium or valproate. [145] [146] Lamotrigine has some efficacy in treating depression, and this benefit is greatest in more severe depression. [147]
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Valproate – Available in extended release form. This drug can be very irritating to the stomach, especially when taken as a free acid. Liver function and CBC should be monitored. [6] Lamotrigine (aka Lamictal) – FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [7]
In the week of December 5, there were 91 outbreaks of norovirus reported, up from 69 the previous week. ... The good news is that most people improve within one to two days and recover completely ...