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Among bipolar patients taking anticonvulsants, those on lamotrigine have a better cognitive profile than those on carbamazepine, valproate, topiramate, and zonisamide. [ 36 ] Although decreased verbal memory and slowed psychomotor speed are common side effects of lithium use [ 37 ] [ 38 ] these side effects usually disappear after ...
Lamotrigine (aka Lamictal) FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition ...
According to guidelines by the American Academy of Neurology and American Epilepsy Society, [42] mainly based on a major article review in 2004, [43] patients with newly diagnosed epilepsy who require treatment can be initiated on standard anticonvulsants such as carbamazepine, phenytoin, valproic acid/valproate semisodium, phenobarbital, or on ...
Switching directly is usually only a safe option for switching between certain SSRIs and SNRIs with short half-lives, as these medications are less likely to cause drug interactions or unwanted ...
Valproate has become a commonly prescribed treatment and effectively treats manic episodes. [147] Carbamazepine is less effective in preventing relapse than lithium or valproate. [148] [149] Lamotrigine has some efficacy in treating depression, and this benefit is greatest in more severe depression. [150]
There was a clear difference between the groups, but the meaning of this in day-to-day care is unclear. MD 5.85 lower (7.8 lower to 3.91 lower) Moderate: Adverse events; Abnormal liver function (blood test changes)* Adding valproate to antipsychotic drug treatment does not clearly cause liver problems.
Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. [ 5 ] [ 8 ] For epilepsy, this includes focal seizures , tonic-clonic seizures , and seizures in Lennox-Gastaut syndrome . [ 8 ]
Ethosuximide is usually well tolerated. [5] Common side effects include loss of appetite, abdominal pain, diarrhea, and feeling tired. [4] Serious side effects include suicidal thoughts, low blood cell levels, and lupus erythematosus. [4] [5] It is unclear if it has adverse effects on the fetus during pregnancy. [4]