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Hunan hand syndrome (also known as "chili burn" [1]) is a temporary, but very painful, cutaneous condition that commonly afflicts those who handle, prepare, or cook with fresh or roasted chili peppers. [1] It was first described in an eponymous case report in The New England Journal of Medicine in 1981. [2]
It is a potent irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related amides (capsaicinoids) are produced as secondary metabolites by chili peppers, likely as deterrents against certain mammals and fungi. [9]
Although the "burning" sensation does not correspond to a real stimulus, repeated and prolonged use of hot spices may harm the peripheral heat-sensing neurons; this mechanism may explain why frequent spice users become less sensitive to both spices and heat. Foods containing capsaicin, like hot sauces, can have different effects on each ...
Why your butt feels like it's on fire after eating chicken wings, hot sauce and other spicy hot foods, and how to relieve the burning feeling.
Not everybody enjoys feeling the burn. But in the tight-knit world of chili heads who compete to see who can eat the most uber-spicy peppers, the endorphin rush that comes from capsaicin — the ...
The best-known activators of TRPV1 are: temperature greater than 43 °C (109 °F); acidic conditions; capsaicin (the irritating compound in hot chili peppers); and allyl isothiocyanate, the pungent compound in mustard and wasabi. [13] The activation of TRPV1 leads to a painful, burning sensation.
There’s also a neurophysiological explanation for why people hurt themselves, said Dr. Vibh Forsythe Cox, director of the Marsha M. Linehan Dialectical Behavior Therapy Clinic at the University ...
Chili peppers are eaten by birds living in the chili peppers' natural range, possibly contributing to seed dispersal and evolution of the protective capsaicin in chili peppers, as a bird in flight can spread the seeds further away from the parent plant after they pass through its digestive system than any land or tree dwelling mammal could do ...