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General structure of an amide (specifically, a carboxamide) Formamide, the simplest amide Asparagine (zwitterionic form), an amino acid with a side chain (highlighted) containing an amide group. In organic chemistry, an amide, [1] [2] [3] also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R ...
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Drug Other common names Image First synthesis Dates of clinical use Chemical/structural class Duration of effect amylocaine: Stovaine 1904 (Ernest Fourneau) ester- benzoic ambucaine [1] diester - aminosalicylic articaine: Astracaine, Septanest, Septocaine, Ultracaine, Zorcaine Amide benzocaine: Anbesol, Orajel Ester - Aminobenzoic Short benzonatate
A lactam is a cyclic amide, and beta-lactams are named so because the nitrogen atom is attached to the β-carbon atom relative to the carbonyl. The simplest β-lactam possible is 2-azetidinone. β-lactams are significant structural units of medicines as manifested in many β-lactam antibiotics . [ 2 ]
Ropivacaine / r oʊ ˈ p ɪ v ə k eɪ n / is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine hydrochloride is commonly marketed by AstraZeneca under the brand name Naropin.
Structures of three kinds of amides: an organic amide (carboxamide), a sulfonamide, and a phosphoramide. In chemistry, the term amide (/ ˈ æ m aɪ d / or / ˈ æ m ɪ d / or / ˈ eɪ m aɪ d /) [1] [2] [3] is a compound with the functional group R n E(=O) x NR 2, where x is not zero, E is some element, and each R represents an organic group or hydrogen. [4]
The structure of nicotinamide consists of a pyridine ring to which a primary amide group is attached in the meta position. It is an amide of nicotinic acid. [7] As an aromatic compound, it undergoes electrophilic substitution reactions and transformations of its two functional groups.
The −OH group is replaced by an −NH 2 group and the =O group is replaced by =N R, giving amidines the general structure R n E(=NR)NR 2. [ 10 ] [ 11 ] [ 12 ] When the parent oxoacid is a carboxylic acid , the resulting amidine is a carboxamidine or carboximidamide ( IUPAC name).