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Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
The outer enamel epithelium, also known as the external enamel epithelium, is a layer of cuboidal cells located on the periphery of the enamel organ in a developing tooth. This layer is first seen during the bell stage. The rim of the enamel organ, where the outer and inner enamel epithelium join is called the cervical loop.
It is widely accepted that there is a factor within the tissues of the first branchial arch that is necessary for the development of teeth. [2] The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3]
Human teeth function to mechanically break down items of food by cutting and crushing them in preparation for swallowing and digesting. As such, they are considered part of the human digestive system. [1] Humans have four types of teeth: incisors, canines, premolars, and molars, which each have a specific function. The incisors cut the food ...
The other dominant hypothesis, the "clone model", proposes that the epithelium programs a group of ectomesenchymal cells to generate teeth of particular shapes. This group of cells, called a clone, coaxes the dental lamina into tooth development, causing a tooth bud to form. Growth of the dental lamina continues in an area called the "progress ...
The cell is rich in endoplasmic reticulum and Golgi complex, especially during primary dentin formation, which allows it to have a high secretory capacity; it first forms the collagenous matrix to form predentin, then mineral levels to form the mature dentin. Odontoblasts form approximately 4 μm of predentin daily during tooth development.
The cells are part of the reduced enamel epithelium after enamel maturation and then subsequently undergo apoptosis before or after tooth eruption. [ 2 ] [ 3 ] : 103 These stages occur during the third and final stage of amelogenesis , called the maturation phase.
The primordium contains each of the primordial tissue types, essential for the development of successive teeth. These primordial tissues together form the enamel organ, dental papilla and dental sac. Also during the cap stage is the formation of a depression within the deepest part of each tooth bud of the dental lamina. The dental lamina is a ...