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  2. Inductive effect - Wikipedia

    en.wikipedia.org/wiki/Inductive_effect

    The inductive effect can be used to determine the stability of a molecule depending on the charge present on the atom and the groups bonded to the atom. For example, if an atom has a positive charge and is attached to a - I group its charge becomes 'amplified' and the molecule becomes more unstable.

  3. Bent's rule - Wikipedia

    en.wikipedia.org/wiki/Bent's_rule

    The inductive effect is the transmission of charge through covalent bonds and Bent's rule provides a mechanism for such results via differences in hybridisation. In the table below, [ 26 ] as the groups bonded to the central carbon become more electronegative, the central carbon becomes more electron-withdrawing as measured by the polar ...

  4. Aromatic ring current - Wikipedia

    en.wikipedia.org/wiki/Aromatic_ring_current

    The effect helps distinguish these nuclear environments and is therefore of great use in molecular structure determination. In benzene, the ring protons experience deshielding because the induced magnetic field has the same direction outside the ring as the external field and their chemical shift is 7.3 parts per million (ppm) compared to 5.6 ...

  5. Field effect (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Field_effect_(chemistry)

    A field effect is the polarization of a molecule through space. The effect is a result of an electric field produced by charge localization in a molecule. [1] This field, which is substituent and conformation dependent, can influence structure and reactivity by manipulating the location of electron density in bonds and/or the overall molecule. [2]

  6. Two-dimensional nuclear magnetic resonance spectroscopy

    en.wikipedia.org/wiki/Two-dimensional_nuclear...

    Heteronuclear correlation spectroscopy gives signal based upon coupling between nuclei of two different types. Often the two nuclei are protons and another nucleus (called a "heteronucleus"). For historical reasons, experiments which record the proton rather than the heteronucleus spectrum during the detection period are called "inverse ...

  7. Fragmentation (mass spectrometry) - Wikipedia

    en.wikipedia.org/wiki/Fragmentation_(mass...

    Fragmentation is a type of chemical dissociation, in which the removal of the electron from the molecule results in ionization. Removal of electrons from either sigma bond, pi bond or nonbonding orbitals causes the ionization. [2] This can take place by a process of homolytic cleavage or homolysis or heterolytic cleavage or heterolysis of the ...

  8. Asymmetric induction - Wikipedia

    en.wikipedia.org/wiki/Asymmetric_induction

    The Cram's rule of asymmetric induction named after Donald J. Cram states In certain non-catalytic reactions that diastereomer will predominate, which could be formed by the approach of the entering group from the least hindered side when the rotational conformation of the C-C bond is such that the double bond is flanked by the two least bulky groups attached to the adjacent asymmetric center. [3]

  9. Markovnikov's rule - Wikipedia

    en.wikipedia.org/wiki/Markovnikov's_rule

    In a titanium(IV) chloride-catalyzed formal nucleophilic substitution at enantiopure 1 in the scheme below, two products are formed – 2a and 2b Due to the two chiral centers in the target molecule, the carbon carrying chlorine and the carbon carrying the methyl and acetoxyethyl group, four different compounds are to be formed: 1R,2R- (drawn ...