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Minimum information about a microarray experiment (MIAME) is a standard created by the FGED Society for reporting microarray experiments. [1]MIAME is intended to specify all the information necessary to interpret the results of the experiment unambiguously and to potentially reproduce the experiment.
The expected response to a given treatment combination is called a cell mean, [12] usually denoted using the Greek letter μ. (The term cell is borrowed from its use in tables of data.) This notation is illustrated here for the 2 × 3 experiment. A contrast in cell means is a linear combination of cell means in which the coefficients sum to 0 ...
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The response variable is measured using a combination of factors at different levels, and each unique combination is known as a run. To reduce the number of runs in comparison to a full factorial, the experiments are designed to confound different effects and interactions, so that their impacts cannot be distinguished.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]