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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
The more active enantiomer, esketamine (S-ketamine), is also available for medical use under the brand name Ketanest S, [135] while the less active enantiomer, arketamine (R-ketamine), has never been marketed as an enantiopure drug for clinical use. While S-ketamine is more effective as an analgesic and anesthetic through NMDA receptor ...
How ketamine therapy is different from recreational use. Ketamine has long been studied for its potential mental health benefits as well, specifically in managing treatment-resistant depression ...
Dr. Mandel: There are about 170 clinical studies on ketamine therapy for depression and other mental health conditions. The results that have been published, about 70 studies, have been ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
In October 2023, the FDA warned about using the substance to treat psychiatric disorders in non-injectable forms, noting that safety concerns that may be associated with ketamine usage include ...
Five subjects dropped out of the ketamine study; of these, four were taking valproate and one was being treated with lithium. One patient showed signs of hypomania following ketamine administration and two experienced low mood. This study demonstrates a rapid-onset antidepressant effect of ketamine in a small group of patients with bipolar ...
At the Boise Ketamine Clinic, the cost of ketamine is $350 per session in lozenge form, which is self-guided with monitoring from a nurse for 40 minutes to an hour, and $600 per session for ...