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16S rRNA (cytosine 967-C 5)-methyltransferase (EC 2.1.1.176, rsmB (gene), fmu (gene), 16S rRNA m5C967 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytosine 967-C 5)-methyltransferase.
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RsmA binds to RsmB regulatory RNA which is also a member of this family. RsmB RNA was shown to be upregulated by GacS/A system, and increase downstream T3SS gene expression. [4] FlhDC, the master regulator of flagellar genes, also activates rsmB RNA production. [5] A regulatory network have been revealed connecting rsmB, FlhDC and T3SS. [6]
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This structure is similar to the CsrB and RsmB regulatory RNAs (CsrB/RsmB RNA family), [1] suggesting this RNA also interacts with a CsrA-like protein. Studies in Legionella pneumophila have shown that the ncRNAs RsmY and RsmZ together with the proteins LetA and CsrA are involved in a regulatory cascade.
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The rsmY RNA family is a set of related non-coding RNA genes, that like RsmZ, is regulated by the GacS/GacA signal transduction system in the plant-beneficial soil bacterium and biocontrol model organism Pseudomonas fluorescens CHA0.
Cocoa was the top-performing commodity of 2024. The price of the bean surged as headwinds battered key producers. Prices are likely to stay high into 2025, analysts at ING said.