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Trimethobenzamide was also available as a rectal suppository, but such formulations were banned by the U.S. Food and Drug Administration on April 6, 2007, due to unproven efficacy. [ 2 ] Synthesis
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid. In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5] It is slightly soluble in water, [2] and soluble in many organic solvents. [6]
It is a benzamide HDI and inhibits Class I HDAC1, HDAC2, HDAC3, as well as Class IIb HDAC10. [ 3 ] Tucidinostat is approved by the Chinese FDA for relapsed or refractory peripheral T-cell lymphoma (PTCL) and has orphan drug status in Japan.
A blister package of Ganaton (Itopride) 50 mg tablets intended for distribution in the Slovak Republic. Typically, itopride is indicated in the treatment of GI symptoms caused by reduced GI motility: dyspepsia of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain) [7] [8] gastroparesis (delayed gastric emptying) [9 ...
Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders like schizophrenia, major depressive disorder, nausea and vomiting, and gastroparesis.
[4] [7] [8] In 2018 it was the first antipoxviral drug approved in the United States. The drug works by blocking cellular transmission of orthopoxviruses, thus preventing disease. [9] Tecovirimat has been effective in laboratory testing; it has been shown to protect animals from mpox and rabbitpox and causes no serious side effects in humans. [6]
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
Fezolinetant, sold under the brand name Veozah among others, is a medication used for the treatment of hot flashes (vasomotor symptoms) due to menopause. [4] [10] It is a small-molecule, orally active, selective neurokinin-3 (NK 3) receptor antagonist which is under development by for the treatment of sex hormone-related disorders.