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Comparison of Helicobacter pylori eradication regimens [8] [9] Regimen Duration, days Drugs used Notes Vonoprazan-amoxicillin dual therapy 7-14 vonoprazan 20 mg bid and amoxicillin 750 mg bid As successful as bismuth-containing quadruple therapy [10] Triple therapy 7–14 PPI (standard dose) bid, amoxicillin 1 g bid and clarithromycin 0.5 g bid
"Analysis of the cost-effectiveness of using vonoprazan-amoxicillin-clarithromycin triple therapy for first-line Helicobacter pylori eradication". Scandinavian Journal of Gastroenterology . 52 (2): 238–241.
The dual therapy of using vonoprazan with amoxicillin has been investigated for the treatment of H. pylori infection [6] and also compared with the triple therapy of using vonoprazan, amoxicillin, and clarithromycin for the eradication of H. pylori infection. [7] Both treatments have been found to be effective.
Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion. The anti-ulcer dosing regimens generally repair ...
Triple-therapy, modernized to a proton pump inhibitor and two antibiotics, soon becomes first line therapy for eradication. World Congress of Gastroenterology recommends eradicating H. pylori to cure duodenal ulcers. [51] First report of resistance of H. pylori to the antibiotic metronidazole. [52] Resistance of H. pylori to treatment will lead ...
Vonoprazan, sold under the brand name Voquezna among others, is a first-in-class potassium-competitive acid blocker medication. [2] [1] Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori.
Triple therapy may refer to : . a first line therapy in Helicobacter pylori eradication protocols; any of the three drug treatments used in Management of HIV/AIDS; the combination of methotrexate, sulfasalazine, and hydroxychloroquine used to treat rheumatoid arthritis
Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape that exhibits less virulence . [ 1 ] [ 2 ] Its helical body (from which the genus name Helicobacter derives) is thought to have evolved to penetrate the mucous lining of the stomach ...
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