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In organic chemistry, isothiocyanate is a functional group as found in compounds with the formula R−N=C=S. Isothiocyanates are the more common isomers of thiocyanates , which have the formula R−S−C≡N .
Phenyl thiocyanate and phenyl isothiocyanate are isomers. Organic thiocyanates are organic compounds containing the functional group RSCN. the organic group is attached to sulfur: R−S−C≡N has a S–C single bond and a C≡N triple bond. [1] Organic thiocyanates are valued building blocks.
Thiocyanic acid is a chemical compound with the formula H S C N and structure H−S−C≡N, which exists as a tautomer with isothiocyanic acid (H−N=C=S). [8] The isothiocyanic acid tautomer tends to dominate with the compound being about 95% isothiocyanic acid in the vapor phase.
Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications [1] [2] including flow cytometry. First described in 1942, [ 3 ] FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (−N=C=S), replacing a hydrogen atom on the bottom ring of the structure.
The topic also includes transition metal complexes of isothiocyanate. These complexes have few applications but played significant role in the development of coordination chemistry. These complexes have few applications but played significant role in the development of coordination chemistry.
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