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Acetamide (systematic name: ethanamide) is an organic compound with the formula CH 3 CONH 2. It is an amide derived from ammonia and acetic acid . It finds some use as a plasticizer and as an industrial solvent. [ 5 ]
It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is very toxic. [1] It is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide. [2] May cause reproductive disorders. If swallowed or in contact with skin, it can cause serious damage and death. Can cause serious ...
Assignment to a toxicity class is based typically on results of acute toxicity studies such as the determination of LD 50 values in animal experiments, notably rodents, via oral, inhaled, or external application. The experimental design measures the acute death rate of an agent.
Reproductive toxicity: 2: Suspected of damaging fertility or the unborn child (H361) Specific target organ toxicity – repeated exposure: 2: May cause damage to organs through prolonged or repeated exposure (H373) Serious eye damage/eye irritation: 2: Causes serious eye irritation (H319) Acute toxicity – inhalation: 3: Toxic if inhaled (H331)
Thioacetamide is known to induce acute or chronic liver disease (fibrosis and cirrhosis) in the experimental animal model. Its administration in rat induces hepatic encephalopathy, metabolic acidosis, increased levels of transaminases, abnormal coagulation, and centrilobular necrosis, which are the main features of the clinical chronic liver disease so thioacetamide can precisely replicate the ...
As a source of amidine, acetamidine hydrochloride is a precursor to the industrial and laboratory synthesis of many nitrogen compounds.It reacts with β-dicarbonyls to produce substituted pyrimidines, [5] with acetaldehydes to form substituted imidazoles, [6] and with imidates to form substituted triazines.
In 40 CFR 156.62, the EPA established four Toxicity Categories for acute hazards of pesticide products, with "Category I" being the highest toxicity category (toxicity class). Most human hazard, precautionary statements, and human personal protective equipment statements are based upon the Toxicity Category of the pesticide product as sold or ...
Acetamide; Dichloroacetamide; N-Chlorosuccinimide; Except where otherwise noted, ... Chloroacetamide is toxic, irritates eyes and skin, and may cause an allergic ...