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Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, [1] [2] is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
A rare form of ocular (eye) involvement in this syndrome is retinal vasculitis which presents with painless decrease of vision with the possibility of floaters or visual field defects. [4] Optic nerve involvement in Behçet's disease is rare, typically presenting as progressive optic atrophy and visual loss.
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
Other general symptoms of Behçet's disease are also present among Parenchymal NBD patients such as genital ulcers, skin lesions and ocular involvement. When the brainstem is affected, ophthalmoparesis , cranial neuropathy , and cerebellar or pyramidal dysfunction may be observed. [ 2 ]
Sweet's syndrome-like dermatosis is a cutaneous condition associated with bowel disorders. [1] See also. Sweet's syndrome; List of cutaneous conditions; References
Birdshot chorioretinopathy may show resistance to treatment. Immunosuppressant therapy along with oral corticosteroid has been somewhat effective in slowing down the progressive inflammation associated with the disorder, preserving visual integrity as much as possible. Long-term use of such medications must be closely monitored, however, due to ...
Intraocular hemorrhage may be caused by physical trauma (direct injury to the eye); ocular surgery (such as to repair cataracts); or other diseases, injuries, or disorders (such as diabetes, hypertension, or shaken baby syndrome). [2] Severe bleeding may cause high pressure inside the eye, leading to blindness.
Dorsal midbrain structures, as in Parinaud's syndrome. Certain parts of the cerebral cortex (including the frontal eye fields), as in stroke. Toxic envenomation by mambas, taipans, and kraits. Thiamine deficiency can cause ophthalmoparesis in susceptible persons; this is part of the syndrome called Wernicke encephalopathy. The causal pathway by ...