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Difethialone is an anticoagulant used as a rodenticide. [1] It is considered a second generation agent. [2] In May 2008, the EPA added restrictions on the sale of difethialone in consumer-use rodenticide products and also for exterior use by commercial applicators. [3] [4]
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Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison.In recent years, it has become one of the world's most widely used pesticides.It is typically used as a rodenticide, but is also used to control larger pests such as possums.
The rodenticide was found to metabolized in the liver. Metabolism is mediated by cytochrome P450 isozymes and ring hydroxylation also appears to be an important biotransformation step. Hydroxylation occurs on the phenyl and indandionyl rings, [ 13 ] these metabolites can then further undergo conjugation with glucuronic acid prior to entering ...
Diphenadione is a vitamin K antagonist that has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents. The chemical compound is an anti-coagulant with active half-life longer than warfarin and other synthetic 1,3-indandione anticoagulants.
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