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According to the International Labour Office (ILO), PMF requires the presence of large opacity exceeding 1 cm (by x-ray). By pathology standards, the lesion in histologic section must exceed 2 cm to meet the definition of PMF. [6] In PMF, lesions most commonly occupy the upper lung zone, and are usually bilateral.
Although they are often very large tumors (up to 40 cm. in diameter), over half are asymptomatic at diagnosis. [5] While some researchers have proposed that a SFT occupying at least 40% of the affected hemithorax be considered a "giant solitary fibrous tumor", [ 6 ] no such "giant" variant has yet been recognized within the most widely used ...
In a radiographic study of almost 2,000 lung cancer patients published 50 years ago, 3.4% of lung carcinomas proved to be cavitated masses, [34] most of which were squamous cell carcinoma. In a number of cases of severe cavitation, the resected tumor remnant consists of only a thin rim of proliferating cells.
Another study concluded that cigarette smoking is the predominant cause of large cell lung cancer. It estimated that the odds ratio associated with smoking two or more packs/day for current smokers is 37.0 in men and 72.9 in women.
Other reported causes include endotracheal tube obstruction (e.g., from patient biting down on tube), tumors/masses compressing the upper airway, choking on foreign objects, strangulation. [ 1 ] [ 5 ] Interestingly, the use of sugammadex to reverse neuromuscular blockade (the mechanism of paralysis during surgery) has also been associated with ...
Basaloid forms of lung carcinoma were first described in the peer-reviewed medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992. [11] They were first recognized as distinct clinicopathological variants of both squamous cell and large cell lung cancers in 1999, within the third revision of the World Health Organization lung tumor typing and classification scheme.
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[citation needed] Treatment of diseases which increase the risk of aspergilloma, such as tuberculosis, may help to prevent their formation. In cases complicated by severe hemoptysis or other associated conditions such as pleural empyema or pneumothorax , surgery may be required to remove the aspergilloma and the surrounding lung tissue by doing ...