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  2. Fexofenadine - Wikipedia

    en.wikipedia.org/wiki/Fexofenadine

    The safety profile of fexofenadine is quite favorable, as no cardiovascular or sedative effects have been shown to occur even when taking 10 times the recommended dose. [25] Research on humans ranges from a single 800-mg dose, to a twice-daily, 690-mg dose for a month, with no clinically significant adverse effects, when compared to a placebo.

  3. Fexofenadine/pseudoephedrine - Wikipedia

    en.wikipedia.org/wiki/Fexofenadine/pseudoephedrine

    It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [ 2 ] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.

  4. Cenobamate - Wikipedia

    en.wikipedia.org/wiki/Cenobamate

    During the trials, doses of 100, 200, and 400 milligrams (mg) daily reduced the number of seizures per 28 days compared with the placebo group. [ 7 ] Society and culture

  5. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    [22] [27] Subsequently, other non-sedating antihistamines like loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) were developed and introduced. [ 22 ] The introduction of the first-generation antihistamines marked the beginning of medical treatment of nasal allergies. [ 28 ]

  6. Ulcerative colitis - Wikipedia

    en.wikipedia.org/wiki/Ulcerative_colitis

    [8] [200] [201] [202] Etrolizumab is a humanized monoclonal antibody that targets the β7 subunit of integrins α4β7 and αEβ7, ultimately blocking migration and retention of leukocytes in the intestinal mucosa. [201] As of early 2022, Roche halted clinical trials for the use of etrolizumab in the treatment of ulcerative colitis. [203]

  7. Terfenadine - Wikipedia

    en.wikipedia.org/wiki/Terfenadine

    Terfenadine acts as a peripherally-selective antihistamine, or antagonist of the histamine H 1 receptor. [3] It is a prodrug, generally completely metabolized to the active form fexofenadine in the liver by the enzyme cytochrome P450 3A4.

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