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  2. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    Since the next ventricular contraction occurs at its regular time, the filling time for the LV increases, causing an increased LV end-diastolic volume. Due to the Frank–Starling mechanism, the next ventricular contraction is more forceful, leading to the ejection of the larger than normal volume of blood, and bringing the LV end-systolic ...

  3. Cardiac cycle - Wikipedia

    en.wikipedia.org/wiki/Cardiac_cycle

    This is the ejection stage of the cardiac cycle; it is depicted (see circular diagram) as the ventricular systole–first phase followed by the ventricular systole–second phase. [2] After ventricular pressures fall below their peak(s) and below those in the trunks of the aorta and pulmonary arteries, the aortic and pulmonary valves close ...

  4. Cardiac conduction system - Wikipedia

    en.wikipedia.org/wiki/Cardiac_conduction_system

    Although the ventricular stimulus originates from the AV node in the wall separating the atria and ventricles, the Bundle of His conducts the signal to the apex. Depolarization propagates through cardiac muscle very rapidly. Cells of the ventricles contract nearly simultaneously. The action potentials of cardiac muscle are unusually sustained.

  5. Cardiac arrest - Wikipedia

    en.wikipedia.org/wiki/Cardiac_arrest

    Ventricular fibrillation is a tachyarrhythmia characterized by turbulent electrical activity in the ventricular myocardium leading to a heart rate too disorganized and rapid to produce any meaningful cardiac output, thus resulting in insufficient perfusion of the brain and essential organs. [58]

  6. Afterload - Wikipedia

    en.wikipedia.org/wiki/Afterload

    Following Laplace's law, the tension upon the muscle fibers in the heart wall is the pressure within the ventricle multiplied by the volume within the ventricle divided by the wall thickness (this ratio is the other factor in setting the afterload). Therefore, when comparing a normal heart to a heart with a dilated left ventricle, if the aortic ...

  7. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    [1] [2] This means that all atrial cells can contract together, and then all ventricular cells. Different shapes of the cardiac action potential in various parts of the heart Rate dependence of the action potential is a fundamental property of cardiac cells and alterations can lead to severe cardiac diseases including cardiac arrhythmia and ...

  8. Chordae tendineae - Wikipedia

    en.wikipedia.org/wiki/Chordae_tendineae

    When the ventricles of the heart contract in ventricular systole, the increased blood pressures in both chambers push the AV valves to close simultaneously, preventing the backflow of blood into the atria. Since the blood pressure in the atria is much lower than that in the ventricles, the flaps attempt to evert to the low pressure regions.

  9. Fourth heart sound - Wikipedia

    en.wikipedia.org/wiki/Fourth_heart_sound

    The fourth heart sound or S 4 is an extra heart sound that occurs during late diastole, immediately before the normal two "lub-dub" heart sounds (S 1 and S 2).It occurs just after atrial contraction and immediately before the systolic S 1 and is caused by the atria contracting forcefully in an effort to overcome an abnormally stiff or hypertrophic ventricle.