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Cannabidiol (CBD) is a phytocannabinoid, ... Side effects of CBD are dose related. [50] Epidiolex documentation lists sleepiness, insomnia and poor quality sleep, ...
pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID) phenylpropanolamine – controls urinary incontinence in dogs
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H4CBD (hydrogenated CBD, tetrahydrocannabidiol) is a cannabinoid that was first synthesized by Alexander R. Todd in 1940 derived from the catalytic hydrogenation of cannabidiol. [ 1 ] H2-CBD and 8,9-dihydrocannabidiol have also been referred to as "hydrogenated CBD", which may cause confusion.
References A ace Slang for the drug acepromazine or acetyl promazine (trade names Atravet or Acezine), which is a sedative : 3 commonly used on horses during veterinary treatment, but also illegal in the show ring. Also abbreviated ACP. action The way a horse elevates its legs, knees, hock, and feet. : 3 Also includes how the horse uses its shoulder, humerus, elbow, and stifle; most often used ...
In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index , [ 21 ] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation.
CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]
Tincture of cannabis, sometimes known as green dragon, is an alcoholic cannabis concentrate.The solubility of THC in ethanol is greater than 1 g/mL. [1]According to the European Medicines Agency (EMA) cannabis tinctures (tincturea) are a type of liquid cannabis extract obtained using ethanol, water, glycerol, propylene glycol and fatty oils as extraction solvents, depending on the type of ...