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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...
[5] [9] Usage of the sustained release dosage form reduces the administration of recurrent doses while maintaining serum dose levels at the therapeutic range (difference between toxic and therapeutic doses), hence improving patient compliance. [5] Some topical gels are fast release gels, which are highly absorbent and can swell rapidly. [5]
One of the primary challenges of endogenous chemically responsive drug delivery is the inability to address or overcome patient heterogeneity. Patient heterogeneity describes the naturally-occurring difference between patient biology, such as differences in tumor pH for the same cancer and blood concentrations of redox reagents. [1]
Osmotic release systems have a number of major advantages over other controlled-release mechanisms. They are significantly less affected by factors such as pH, food intake, GI motility, and differing intestinal environments. Using an osmotic pump to deliver drugs has additional inherent advantages regarding control over drug delivery rates.
Despite its doggy cuteness, the video does make us wonder: Is ice cream even good for pups? Dog Food Advisor insists it depends on each individual dog and his or her ability to digest lactose in ...
Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...
Trolamine salicylate (Aspercreme, Aspergel) is an organic compound with the chemical formula [HN(CH 2 CH 2 OH) 3] + C 6 H 4 (OH)(COO −).It is a salt of triethanolamine and salicylic acid, i.e. the compound consists of protonated triethanolamine and the conjugate base of salicylic acid, salicate.
But on May 21, the New York City-bred ice cream company announced the launch of its first-ever ice cream for dogs in collaboration with Ollie, a dog food brand making human-grade meals for pups.