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The primary sites of end-target organ damage following an increase in arterial stiffness are the heart, the brain (stroke, white matter hyperintensities (WMHs)), the placenta, and the kidneys (age-related loss of kidney function). [21] Firstly, stiffened arteries compromise the Windkessel effect of the arteries. [22]
The arterial compliance - the amount of tension produced per stretch of arteries, decreases with age, and the stiffness of arteries increases with age. [3] The structural change in blood vessels causes the elderly to be more susceptible to hypertension, which leads to complications in arteries, the heart and even the brain. [citation needed]
There is a recurrent acute and chronic inflammation and thrombosis of arteries and veins of the hands and feet. The main symptom is pain in the affected areas, at rest and while walking (claudication). [1] The impaired circulation increases sensitivity to cold. Peripheral pulses are diminished or absent. There are color changes in the extremities.
Discoloration of the hands, one hand colder than the other hand, weakness of the hand and arm muscles, and tingling are commonly present. [citation needed] Only 1% of people with carpal tunnel syndrome have concomitant TOS. [7] Repetitive motions can cause enlargement of muscles which causes compression of veins.
It can cause the affected limb to swell, and cause pain and an overlying skin rash. In the worst case, a deep vein thrombosis can extend, or a part of a clot can break off as an embolus and lodge in a pulmonary artery in the lungs, known as a pulmonary embolism .The decision to treat deep vein thrombosis depends on its size, a person's symptoms ...
The most common cause is coronary artery disease. Heart attacks are medical emergencies that require immediate medical attention, although some heart attacks can be “silent” and go undetected ...
Peripheral artery disease (PAD) is a form of peripheral vascular disease. Vascular refers to both the arteries and veins within the body. PAD differs from peripheral veinous disease. PAD means the arteries are narrowed or blocked—the vessels that carry oxygen-rich blood as it moves away from the heart to other parts of the body.
Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). [1] This also refers to the condition of damage or rupture of small blood vessels. The best known and most prevalent angiopathy is diabetic angiopathy , a common complication of chronic diabetes .
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