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MRI contrast agents are contrast agents used to improve the visibility of internal body structures in magnetic resonance imaging (MRI). [1] The most commonly used compounds for contrast enhancement are gadolinium -based contrast agents (GBCAs). Such MRI contrast agents shorten the relaxation times of nuclei within body tissues following oral or ...
A contrast agent(or contrast medium) is a substanceused to increase the contrastof structures or fluids within the body in medical imaging.[1] Contrast agents absorb or alter external electromagnetismor ultrasound, which is different from radiopharmaceuticals, which emit radiationthemselves. In X-rayimaging, contrast agents enhance the ...
Iodinated contrast contains iodine.It is the main type of radiocontrast used for intravenous administration.Iodine has a particular advantage as a contrast agent for radiography because its innermost electron ("k-shell") binding energy is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography.
Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle -structured gadolinium-based MRI contrast agent (GBCA). It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4][5] The paramagnetic property of gadoteric acid reduces ...
MRI without contrast agents is the imaging mode of choice for pre-surgical, in-utero diagnosis and evaluation of fetal tumors, primarily teratomas, facilitating open fetal surgery, other fetal interventions, and planning for procedures (such as the EXIT procedure) to safely deliver and treat babies whose defects would otherwise be fatal. [52] [53]
Iodinated contrast. Contrast CT of a patient with brain metastases from breast cancer, before (left) and after (right) injection of iodinated contrast. Iodinated contrast is a form of water-soluble, intravenous radiocontrast agent containing iodine, which enhances the visibility of vascular structures and organs during radiographic procedures.
Nephrogenic systemic fibrosis is a rare syndrome that involves fibrosis of the skin, joints, eyes, and internal organs. NSF is caused by exposure to gadolinium in gadolinium-based MRI contrast agents (GBCAs) in patients with impaired kidney function. [1][2] Epidemiological studies suggest that the incidence of NSF is unrelated to gender or ...
Contrast-enhanced magnetic resonance angiography uses injection of MRI contrast agents and is currently the most common method of performing MRA. [2] [6] The contrast medium is injected into a vein, and images are acquired both pre-contrast and during the first pass of the agent through the arteries. By subtraction of these two acquisitions in ...