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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Medical cannabis can be administered through various methods, including capsules, lozenges, tinctures, dermal patches, oral or dermal sprays, cannabis edibles, and vaporizing or smoking dried buds. Synthetic cannabinoids are available for prescription use in some countries, such as synthetic delta-9-THC and nabilone.
There is significant variation in medical cannabis laws from state to state, including how it is produced and distributed, how it can be consumed, and what medical conditions it can be used for. [2] The first state to effectively legalize medical cannabis was California in 1996, when voters approved Proposition 215 by a 56–44 margin.
Age. The risk of most causes of joint pain increases with age. This may be due to increased wear and stress on joints over time and a higher likelihood of other underlying medical conditions ...
Marihuana prensada ('pressed marijuana') is a cannabis-derived product widespread among the lower classes of South America, [185] especially from the 90s. Locally it is known as "paraguayo" or "paragua", since its main producer is Paraguay. [186] Marijuana is dried and mixed with binding agents that make it toxic and highly harmful to health. [187]
Marijuana kills brain cells; Marijuana causes amotivational syndrome; Marijuana impairs memory and cognition; Marijuana causes psychological impairment; Marijuana interferes with male and female sex hormones; Marijuana use during pregnancy damages the fetus; Marijuana impairs the immune system; Marijuana is more damaging to the lungs than tobacco
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Consequently, a high-fat meal increases levels of 11-hydroxy-THC by only 25% and most of the increase in bioavailability is due to increased levels of THC. [ 31 ] The bioavailability of THC when smoking or inhaling is approximately 25%, with a range of 2% to 56% (although most commonly between 10 and 35%).