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Triple-negative breast cancer (TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor is negative on all three tests giving the name triple-negative). [1]
To be eligible for the MammaPrint gene expression profile, a breast cancer should have the following characteristics: stage 1 or 2, tumor size less than 5.0 cm, estrogen receptor positive (ER+) or estrogen receptor negative (ER-).
This is an accepted version of this page This is the latest accepted revision, reviewed on 30 December 2024. There is 1 pending revision awaiting review. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted ...
Breast cancer is the most common cancer in women worldwide, and can, rarely, also occur in men. There are many different types of breast cancer, of which triple-negative breast cancer is one of ...
Triple negative breast cancer, in particular, has a worse prognosis and can be difficult to treat. There are few targeted therapies like there are for estrogen positive breast cancers, she says ...
You can also expect luminal B cancer to be progesterone receptor-negative, meaning it won't respond very well to hormone therapy. "About 15-20% of breast cancers are luminal B tumors," according ...
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