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An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
A cat hair showing agouti coloration A domestic rabbit with agouti coloration. Agouti is a type of fur coloration in which each hair displays two or more bands of pigmentation. [1] [2] The overall appearance of agouti fur is usually gray or dull brown, [3] although dull yellow is also possible.
Various polygenes (sets of related genes), epigenetic factors, or modifier genes, as yet unidentified, are believed to result in different phenotypes of coloration, some deemed more desirable than others by fanciers. The genetic influences on tipped or shaded cats are: Agouti gene. Tabby pattern genes (such as T a masking the tabby pattern).
A change at the agouti locus is capable of turning bay to black, while a mutation at the extension locus can turn bay or black to chestnut. These three "base" colors can be affected by any number of dilution genes and patterning genes. The dilution genes include the wildtype dun gene, believed to be one of the oldest colors extant in horses and ...
The agouti gene in mice is largely responsible for determining coat colour. The wild-type allele produces a blend of yellow and black pigmentation in each hair of the mouse. This yellow and black blend may be referred to as 'agouti' in colour. [3] One of the mutant alleles of the agouti gene
The gene that makes a cat orange or black is located on the X chromosome. Male cats therefore need only one copy of this gene, while females need both of their X chromosomes to be coded for orange ...
Agouti (coloration), fur coloration in which each hair has alternating dark and light bands; Agouti-signalling protein or ASIP, a circulating hormone encoded by the agouti gene that acts as an antagonist at melanocortin receptors; Agouti-related peptide, a neuropeptide produced in the brain by the AgRP/NPY neuron