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Microangiopathy (also known as microvascular disease, small vessel disease (SVD) or microvascular dysfunction) is a disease of the microvessels, small blood vessels in the microcirculation. [1] It can be contrasted to macroangiopathies such as atherosclerosis , where large and medium-sized arteries (e.g., aorta , carotid and coronary arteries ...
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
Vascular dementia can be caused by ischemic or hemorrhagic infarcts affecting multiple brain areas, including the anterior cerebral artery territory, the parietal lobes, or the cingulate gyrus. [5] On rare occasion, infarcts in the hippocampus or thalamus are the cause of dementia. [ 12 ]
A transient ischemic attack (TIA) is also called a “mini stroke”. ... Ranolazine for coronary microvascular disease. ... the main blood vessel that carries blood to your brain. Your doctor ...
Brain ischemia is insufficient blood flow to the brain, and can be acute or chronic. Acute ischemic stroke is a neurological emergency typically caused by a blood clot blocking blood flow in a vessel in the brain. [15] Chronic ischemia of the brain may result in a form of dementia called vascular dementia. [16]
Microinfarcts may be the second most important cause of dementia, after Alzheimer's disease. [3] [4] Microinfarcts are microscopic lesions, of cellular death or tissue necrosis, which are a result of pathologies involving small vessels. Such pathologies are arteriosclerosis or cerebral amyloid angiopathy. [5]
Ischemia is the loss of blood flow to the focal region of the brain. This produces heterogeneous areas of ischemia at the affected vascular region, furthermore, blood flow is limited to a residual flow. Regions with blood flow of less than 10 mL/100 g of tissue/min are core regions (cells here die within minutes of a stroke).
It may imitate, and is in turn imitated by, a number of other diseases that affect the blood vessels of the brain diffusely such as fibromuscular dysplasia and thrombotic thrombocytopenic purpura. [3] Primary CNS vasculitis has an incidence of 2.4 cases per 1 million people, with an associated mortality of 8-23% and a 25% risk of severe ...