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Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.
The most common side effects are related to the digestive system such as gas, bloating, nausea, diarrhea, or stomach cramps, says Dr. Gupta. “Sometimes that just means the dose was too high for ...
Metformin itself isn’t thought to cause hair loss, but type 2 diabetes and PCOS (polycystic ovary syndrome) — the conditions it’s prescribed to treat — can cause hair loss.
Moreover, abdominal pain is common and may be severe. [15] [10] The level of consciousness is typically normal until late in the process, when lethargy may progress to coma. [12] [8] Ketoacidosis can easily become severe enough to cause hypotension, shock, and death. [8]
Based on the physiological cause of NC, it is projected that the symptoms of NC can worsen over time, with roughly one-third of patients showing signs of improvement with time. [7] For NC patients that develop worse symptoms over time, severe consequences can occur. Over time, untreated NC and LSS can lead to chronic pain and muscle weakness. [13]
The pain from these contractions can cause mobility limitations and a tense feeling within the muscle, he says. While they’re usually harmless, muscle cramps are undoubtedly uncomfortable.
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