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Germ cell tumor (GCT) is a neoplasm derived from the primordial germ cells. [1] Germ-cell tumors can be cancerous or benign. ... and have a lower five-year survival ...
Relative incidences of testicular tumors, showing seminoma at bottom left. [2] A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages. [3]
An extracranial germ cell tumor (EGCT) occurs in the abnormal growth of germ cells in the gonads (testes or ovaries) and the areas other than the brain via tissue, lymphatic system, or circulatory system. The tumor can be benign or malignant (cancerous) by its growth rate.
For other regions, the incidence rates reported are 2.5% in Oceania, 2.0% in North America and 1.3% in Europe. [3] The five-year survival rates have reached up to 90-92%, which is much higher than that of epithelial ovarian cancers. [33] The main reason is the high effectiveness of platinum-based chemotherapy. [1]
Germ cell tumors of unknown type. ... While treatment success depends on the stage, the average survival rate after five years is around 95%, and stage 1 cancer cases ...
Dysgerminoma is the most common type of malignant germ-cell ovarian cancer. Dysgerminoma usually occurs in adolescence and early adult life; about 5% occur in prepubertal children. Dysgerminoma is extremely rare after age 50. It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation ...
A teratoma is a tumor of germ cell origin, containing tissues from more than one germ cell line, [2] [3] [4] It can be ovarian or testicular in its origin. [4] and are almost always benign. [5] An immature teratoma is thus a very rare tumor, representing 1% of all teratomas, 1% of all ovarian cancers, and 35.6% of malignant ovarian germ cell ...
Germ cell tumors other than dysgerminomas have a poor prognosis when they relapse, with a 10% long-term survival rate. [32] Low malignant potential tumors rarely relapse, even when fertility-sparing surgery is the treatment of choice. 15% of LMP tumors relapse after unilateral surgery in the previously unaffected ovary, and they are typically ...