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The stimulants are the first line of treatment for ADHD, with proven efficacy, but they do fail in up to 20% of cases, even in patients without tic disorders. [270] Current prescribed stimulant medications include: methylphenidate, dextroamphetamine, and mixed amphetamine salts . Other medications can be used when stimulants are not an option.
For people who cannot be treated with stimulants due to a substance use disorder or other contraindications, atomoxetine is the suggested first-line treatment in the UK. In Canada, clinical guidelines suggest that first-line treatment be methylphenidate or lisdexamfetamine. [47] Non-stimulant medications are generally second-line treatments in ...
Myasthenia gravis affects 50 to 200 people per million. [3] [4] It is newly diagnosed in 3 to 30 people per million each year. [13] Diagnosis has become more common due to increased awareness. [13] Myasthenia gravis most commonly occurs in women under the age of 40 and in men over the age of 60. [1] [5] [14] It is uncommon in children. [1]
"Treatment options focus on managing symptoms and improving quality of life," says Hesterlee. "With appropriate treatment, many people with myasthenia gravis can manage their symptoms effectively ...
Amifampridine is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The free base form of the drug has been used to treat congenital myasthenic syndromes and Lambert–Eaton myasthenic syndrome (LEMS) through compassionate use programs since the 1990s and was recommended as a first line treatment for LEMS in 2006, using ad hoc forms of the drug, since there was ...
Methylphenidate, sold under the brand names Ritalin (/ ˈ r ɪ t ə l ɪ n / RIT-ə-lin) and Concerta (/ k ə n ˈ s ɜːr t ə / kən-SUR-tə) [citation needed] among others, is a central nervous system (CNS) stimulant to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Diseases of the motor end plate include myasthenia gravis, a form of muscle weakness due to antibodies against acetylcholine receptor, [13] [14] and its related condition Lambert–Eaton myasthenic syndrome (LEMS). [15] Tetanus and botulism are bacterial infections in which bacterial toxins cause increased or decreased muscle tone, respectively ...
About Myasthenia Gravis . Myasthenia gravis (MG) is a chronic autoimmune disorder that causes disabling muscle weakness and fatigue. For most people with MG, the disease is characterized by the presence of antibodies against the acetylcholine receptor, a protein found on the surface of nerve cells that plays a key role in muscle contraction.
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