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Liquefactive necrosis (or colliquative necrosis) is a type of necrosis which results in a transformation of the tissue into a liquid viscous mass. [1] Often it is associated with focal bacterial or fungal infections, and can also manifest as one of the symptoms of an internal chemical burn . [ 2 ]
A myocardial infarction may compromise the function of the heart as a pump for the circulation, a state called heart failure. There are different types of heart failure; left- or right-sided (or bilateral) heart failure may occur depending on the affected part of the heart, and it is a low-output type of failure.
[2] [3] Coronary artery ectasia occurs 4 times more frequently in males than in females and in people who have risk factors for heart disease such as smokers. [ 1 ] [ 4 ] [ 5 ] While the disease is commonly found in patients with atherosclerosis and coronary artery disease, it can occur by itself and in both cases, it can cause health problems.
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. [9] Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7] Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. [10]
Ischemic coagulative necrosis results and fibrosis of the affected area develops from the reparative response beginning at the preserved margins and working its way inwards. One exception to coagulative necrosis is the brain, which undergoes liquefactive necrosis in response to infarction. [citation needed]
In coronary heart disease, the coronary arteries narrow due to the buildup of atheroma or fatty deposits on the vessel walls. The atheroma causes the blood flow of the arteries to be restricted. [6] By restricting the blood flow, the tissue is still receiving some oxygen, but not enough to sustain the tissue over time. [5]
Symptoms include chest pain or angina, shortness of breath, and fatigue. [6]A completely blocked coronary artery will cause a heart attack. [6] Common heart attack symptoms include chest pain or angina, pain or discomfort that spreads to the shoulder, arm, back, neck jaw, teeth or the upper belly, cold sweats, fatigue, heartburn, nausea, shortness of breath, or lightheadedness.
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