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  2. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    Wyeth pantoprazole 20 mg (Protonix®) Vial of generic pantoprazole for IV administration. The mechanism of action of pantoprazole is to inhibit the final step in gastric acid production. [15] In the gastric parietal cell of the stomach, pantoprazole covalently binds to the H+/K+ ATP pump to inhibit gastric acid and basal acid secretion. [15]

  3. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Pantoprazole was first prepared in April 1985 by a small group of scale-up chemists. It is a dimethoxy-substituted pyridine bound to a fluoroalkoxy substituted benzimidazole. [5] Pantoprazole sodium is available as gastroresistant or delayed release tablets and as lyophilized powder for intravenous use.

  4. Pulmonary drug delivery - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_drug_delivery

    Pulmonary drug delivery is a route of administration in which patients use an inhaler to inhale their medications and drugs are absorbed into the bloodstream via the lung mucous membrane. This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD) .

  5. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    [20] [21] [22] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC, should be used no more than three 14-day treatment courses over one year. [23] [24] Despite their extensive use, the quality of the evidence supporting their use in some of these conditions is variable.

  6. Rate of infusion - Wikipedia

    en.wikipedia.org/wiki/Rate_of_infusion

    In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.

  7. Postmaster spars with Georgia congressman during contentious ...

    www.aol.com/postmaster-spars-georgia-congressman...

    At one point, the on-time delivery rate was in the 40% range. DeJoy said in a Senate hearing last Postmaster spars with Georgia congressman during contentious hearing

  8. Florida Drug Deaths Rose Dramatically as Pam Bondi Did Her ...

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    The age-adjusted rate of "deaths from drug poisoning" did fall a bit after she took office, from 13.7 per 100,000 residents in 2011 to 12.1 in 2013. ... Snow falls along I-95 corridor from ...

  9. Absorption (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Absorption_(pharmacology)

    Zero-order absorption: rate of absorption is constant. A common example is continuous intravenous infusion. First-order absorption: rate of absorption is proportional to the amount of drug remaining to be absorbed. Representative examples include typical cases of oral administration, subcutaneous injection, and intramuscular injection.

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