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Glaucoma medication is divided into groups based on chemical structure and pharmacologic action. The goal of currently available glaucoma therapy is to preserve visual function by lowering intraocular pressure (IOP) in patients that have an increased intraocular pressure.
Ocular hypertension is treated with either medications (eye drops), surgery, or laser. Treatment, by lowering the intraocular pressure, may help decrease the risk of vision loss and damage to the eye from glaucoma. Treatment options include pressure-lowering 'antiglaucomatous' eye drops, surgery, and/or laser eye surgery. [4]
Glaucoma is a group of eye diseases that can lead to damage of the optic nerve. The optic nerve transmits visual information from the eye to the brain. Glaucoma may cause vision loss if left untreated. It has been called the "silent thief of sight" because the loss of vision usually occurs slowly over a long period of time. [5]
Alirocumab, sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. It is a human monoclonal antibody that belongs to a novel class of anti-cholesterol drugs, known as PCSK9 inhibitors , and it was the first such agent ...
A 3x rise in intraocular pressure after an intravitreal injection is expected and usually only lasts a few minutes. [10] Studies have shown an increased risk of sustained elevated intraocular pressure due to repeated intravitreal injections. [6] Elevated intraocular pressure leads to tissue damage, this is how glaucoma damages the eye.
If IOP is not so high, medical therapy with aqueous suppressants is preferred. [3] Surgery is advised if the intraocular pressure remains in 40- to 50-mm Hg range even after medical therapy. [ 3 ] Anterior chamber can be cleaned by making a small paracentesis in the cornea and irrigating the anterior chamber with a saline solution . [ 3 ]
Angle-closure glaucoma should be considered if there is painful loss of vision with a red eye, nausea or vomiting. [4] The eye pressure will be very high typically greater than 40 mmHg. [5] Emergent laser treatment to the iris may prevent blindness. [4]
Post-traumatic glaucoma: Trauma to the eye is often observed to cause secondary glaucoma. The incidence is notably higher in populations with increased levels of physical activity. [2] Ghost-cell glaucoma: Ruptured red blood cells will release haemoglobin in the form of Heinz bodies, which are potent in increasing the IOP level. [2]
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