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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
PSA was launched in July 1991 by David Hall, owner of the coin grading company Professional Coin Grading Service (PCGS), to serve collectors as a third-party card grader. [1] At the outset, the business faced difficulties owing to a limited demand from collectors who sought card grading services. [ 2 ]
If three patterns are seen, the first number of the score would be the primary grade and the second number the pattern with the highest grade. For example, if the primary tumor grade was 2 and the secondary tumor grade was 3 but some cells were found to be grade 4, the Gleason score would be 2+4=6.
A PSA of 4 nanograms per milliliter (ng/mL) is typically the cutoff that doctors use to recommend more testing, according to the American Cancer Society. If your levels are between 4 ng/mL and 10 ...
On his doctor’s urging, Steves had taken a prostate-specific antigen blood test (PSA) for the first time ever. “That probably saved my life,” he says. “That probably saved my life,” he says.
It is determined by collecting data from vast numbers of laboratory tests. [citation needed] Plasma or whole blood ... (PSA) 40–49 years: 1.2–2.9 [75] μg/L ...
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