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Nodular goiter is an enlarged thyroid gland with bumps (nodules) on it. It is associated with both high and low activity of the gland. Toxic multinodular goitre, also ...
Nodular goitres are either of one nodule (uninodular) or of multiple nodules (multinodular). [14] Multinodular goiter (MNG) is the most common disorder of the thyroid gland. [15] Growth pattern. Uninodular goitre: one thyroid nodule; can be either inactive, or active (toxic) – autonomously producing thyroid hormone.
Toxic multinodular goiter (TMNG), also known as multinodular toxic goiter (MNTG), is an active multinodular goiter associated with hyperthyroidism.. It is a common cause of hyperthyroidism [2] [3] in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH).
Colloid nodules, also known as adenomatous nodules [1] or colloid nodular goiter [2] are benign, noncancerous enlargement of thyroid tissue. [3] Although they may grow large, and there may be more than one, they are not malignant and they will not spread beyond the thyroid gland. Colloid nodules are the most common kind of thyroid nodule. [4]
A goiter is an abnormal thyroid gland proliferation that manifests as multi-nodular, uni-nodular, or non-nodular diffuse glandular enlargement. A goiter is formed of solid matrix, colloid cysts, blood products, calcification, and fibrosis, and this heterogeneity may lead to variable appearances on a CT scan (Figs. 13, 1414 and and15)15).
The goiter in Graves disease is often not nodular, but thyroid nodules are also common. [19] Differentiating common forms of hyperthyroidism such as Graves' disease, single thyroid adenoma, and toxic multinodular goiter is important to determine proper treatment. [19]
Hyperthyroidism has also been linked to an enlarged thyroid gland (goiter), irregular menstrual cycles, high blood pressure, brittle hair, and more prominent eyes, per Johns Hopkins Medicine.
Rarely goiters can cause compression of the airway, compression of the vessels in the neck, or difficulty swallowing. [7] Tumors, often called thyroid nodules, can also have many different symptoms ranging from hyperthyroidism to hypothyroidism to swelling in the neck and compression of the structures in the neck. [7]