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  2. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Antidepressant discontinuation syndrome; Other names: Antidepressant withdrawal syndrome [1] Specialty: Psychiatry: Symptoms: Flu-like symptoms, trouble sleeping, anxiety, depression, dissociation, intrusive thoughts, nausea, poor balance, dizziness, sensory changes [2] Usual onset: Within 3 days [2] Duration: Few weeks to months [3] [4] Causes

  3. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    Post-acute withdrawal syndrome (PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [1] [2] opiates, benzodiazepines, antidepressants, and other substances. [3] [4] [5] Infants born to mothers who used substances of dependence during pregnancy may also experience a PAWS.

  4. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Repeated benzodiazepine withdrawal episodes may result in similar neuronal kindling as that seen after repeated withdrawal episodes from alcohol, with resultant increased neuro-excitability. The glutamate system is believed to play an important role in this kindling phenomenon with AMPA receptors which are a subtype of glutamate receptors being ...

  5. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    Acute withdrawal syndromes can last days, weeks or months. Protracted withdrawal syndrome, also known as post-acute-withdrawal syndrome or "PAWS", is a low-grade continuation of some of the symptoms of acute withdrawal, typically in a remitting-relapsing pattern, often resulting in relapse and prolonged disability of a degree to preclude the ...

  6. Serotonin syndrome - Wikipedia

    en.wikipedia.org/wiki/Serotonin_syndrome

    It can take at least four weeks for this enzyme to be replaced by the body in the instance of irreversible inhibitors. [31] With respect to tricyclic antidepressants, only clomipramine and imipramine have a risk of causing SS. [32] Many medications may have been incorrectly thought to cause SS.

  7. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Some of the symptoms that could possibly occur as a result of a withdrawal from benzodiazepines after long-term use include emotional clouding, [1] flu-like symptoms, [5] suicide, [11] nausea, headaches, dizziness, irritability, lethargy, sleep problems, memory impairment, personality changes, aggression, depression, social deterioration as ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Two weeks after graduating from the program, she fatally overdosed in a gas station bathroom. For all the people who graduate from 12-step and abstinence-based programs and then relapse, many more drop out before completing them. Recovery Kentucky facilities across the state admitted to HuffPost dropout rates as high as 75 percent.

  9. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Kidney injury. [3] Thioridazine (Melleril) 2005 Germany, UK Withdrawn worldwide due to severe cardiac arrhythmias [64] [65] Continues to be available in Russia. Ticrynafen (Tienilic acid) 1980 Germany, France, UK, US others Liver toxicity and death. [3] Tolcapone (Tasmar) 1998 European Union, Canada, Australia Hepatotoxicity [3] Tolrestat ...